HCID 22989894, compound → HCID 86758285, compound

Participants

Reaction Steps

Synthesis was performed from (2S)-2-({(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoyl}amino)-3-[3-(methoxycarbonyl)4-(2-methoxy-2-oxoethoxy)phenyl]propanoic acid (91 mg, 0.16 mmol) and 4-[(aminooxy)methyl]-1,1′-biphenyl hydrochloride (46 mg, 0.20 mmol) according to Method C with HPLC purification to give the title compound (47 mg). 1H-NMR (400 MHz, CD3OD-Me2SO-d6) d 7.74-7.16 (17H), 4.84 (1H), 4.76 (1H), 4.64 (s, 2H), 4.32 (m, 1H), 3.03 (m, 3H), 1.41 (s, 9H); IR (KBr) 3272, 2978, 1681, 1652 cm−1; HRMS m/z 711.2831 (calc. of monoisotopic mass for C39H41N3O10 gives 711.2792).

Provenance & Evidence