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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2188461Generated: October 29, 2026

HCID 12261881, compound → HCID 70159572, compound

https://huagongshe.com/reaction/2188461

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 12261881HCID 12261881—
Reactant(2S)-2-({(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoyl}amino)-3-[3-(methoxycarbonyl)-4-(2-methoxy-2-oxoethoxy)phenyl]propanoic acidHCID 57019224—
ProductHCID 70159572HCID 7015957226.3%

Reaction Steps

Synthesis was performed from (2S)-2-({(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoyl}amino)-3-[3-(methoxycarbonyl)-4-(2-methoxy-2-oxoethoxy)phenyl]propanoic acid (88 mg, 0.16 mmol) and 1-methyl-3,3-diphenylpropylamine (45 mg, 0.19 mmol) according to Method C with HPLC purification to give the title compound (31 mg) as a diastereomeric mixture in a 2:1 ratio. HRMS m/z 737.3312 (calc. of monoisotopic mass for C42H47N3O9 gives 737.3329).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06410585B1
Source datasetuspto-grants-2002_06
ORD IDord-8203f1b1e6034ca8a72377b6e2a78f49
Source noteuspto-grants-2002_06