1-(2-Fluorophenyl)-1,3-propanediamine → 1-Phenylpropane-1,3-diamine

HRID 2188475Notes

Reaction equation

HRID 2188475 reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([NH2:12])[CH2:9][CH2:10][NH2:11].CC1C=CC=CC=1C(N)CCN.ClC1C=CC=CC=1C(N)CCN>>[C:3]1([CH:8]([NH2:12])[CH2:9][CH2:10][NH2:11])[CH:4]=[CH:5][CH:6]=[CH:7][CH:2]=1

Participants

4

Reactant 3

HCID 223465761-(2-Fluorophenyl)-1,3-propanediamineHCID 223466381-(2-Chlorophenyl)-1,3-propanediamineHCID 223466481-(2-Methylphenyl)-1,3-propanediamine

Product 1

HCID 130345451-Phenylpropane-1,3-diamine

Procedure

Analogously, 1-(2-fluorophenyl)-1,3-propanediamine, 1-(2-methylphenyl)-1,3-propanediamine and 1-(2-chlorophenyl)-1,3-propanediamine have been prepared by using the above procedure and the appropriate starting material.

Sources & evidence

ORD record
ord-f6ff0ed640364a11b8418f43821f1b09
Source dataset
uspto-grants-2002_06
Patent number
US06410729B1

Reaction notes

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