HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dimethoxyethane → HCID 24891682, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dimethoxyethane | HCID 8071 | — |
| Reactant | Dibutyltin oxide | HCID 61221 | — |
| Reactant | Azidotrimethylsilane | HCID 78378 | — |
| Reactant | HCID 24891633 | HCID 24891633 | — |
| Product | HCID 24891682 | HCID 24891682 | — |
Reaction Conditions
| Temperature | 140 °C |
|---|
Reaction Steps
The following heteroaryl substituted phenyl compound can be prepared from {[5-(3-cyano-phenyl)-3-hydroxy-pyridine-2-carbonyl]-amino}acetic acid methyl ester by treatment with trimethylsilyl azide and di-butyl tin oxide in DME and heating the mixture to 140° C., 150 W, 200 psi in a microwave reactor.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08323671B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-062db9925aa24781930210f38604e13f |
| Source note | uspto-grants-2012_12 |