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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2188570Generated: October 29, 2026

2-(4-oxocyclohexyl)-2,3-dihydro-1H-isoindole-1,3-dione → HCID 49763093, compound

https://huagongshe.com/reaction/2188570

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-oxocyclohexyl)-2,3-dihydro-1H-isoindole-1,3-dioneHCID 11998391—
ReactantN-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamideHCID 59361594—
ProductHCID 49763093HCID 49763093—

Reaction Steps

The title compounds were prepared as white solids from the reductive amination of 2-(4-oxo-cyclohexyl)-isoindole-1,3-dione (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in Example 2 Step C) using the procedure described in Step D of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324186B2
Source datasetuspto-grants-2012_12
ORD IDord-5cca5011fe7240d4aad537bb429f7741
Source noteuspto-grants-2012_12