HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 1-(4-Methoxyphenyl)-2,2-dimethylcyclopropanecarbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 1-(4-Methoxyphenyl)-2,2-dimethylcyclopropanecarboxylic acid | HCID 45791023 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 1-(4-Methoxyphenyl)-2,2-dimethylcyclopropanecarbonyl chloride | HCID 59165866 | — |
Reaction Steps
A mixture of 1-(4-methoxyphenyl)-2,2-dimethylcyclopropanecarboxylic acid (44 mg, 0.20 mmol), thionyl chloride (44 μL, 0.60 mmol) and DMF (1 drop) was stirred at room temperature for 30 minutes. The mixture was concentrated and the resultant acid chloride was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324207B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-b9be44101d3b49a3b6ab3ddfdd29b7d3 |
| Source note | uspto-grants-2012_12 |