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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218895Generated: October 25, 2026

1H-Imidazole-1-propanamine → 3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(1H-imidazol-1-yl)propyl]isonicotinamide

https://huagongshe.com/reaction/218895

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Imidazole-1-propanamineHCID 78736—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
Product3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(1H-imidazol-1-yl)propyl]isonicotinamideHCID 11712404—

Reaction Steps

3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(1H-imidazol-1-yl)propyl]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.40 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.60 mmol of 3-imidazol-1-yl-propylamine. LC/MS [4.82 min; 466 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198457B2
Source datasetuspto-grants-2012_06
ORD IDord-c3201d94032e425a8cb8bc934035939d
Source noteuspto-grants-2012_06