Resorcinol → HCID 58280230, compound

Participants

Reaction Steps

Heat 500 mg (1.49 mmol) of 4-chloro-5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidine, 654 mg (5.94 mmol) of resorcinol and 726 mg (2.23 mmol) of caesium carbonate in 10 ml of DMF to 120° C. for 2 h. After cooling, filter and purify the filtrate directly by means of preparative HPLC. Stir the resulting product with dichloromethane, filter with suction, wash with dichloromethane and dry under reduced pressure. 171.4 mg (27% of theory) of the target product are obtained as a beige solid.

Provenance & Evidence