反应详情

Initially charge 715 mg (3.2 mmol) of 4-(2-nitrophenyl)butanoic acid methyl ester in 1.5 ml of ethanol, add 34 mg of palladium on activated carbon (10%) under argon and stir under a hydrogen atmosphere (standard pressure) at RT overnight. In order to complete the reaction, add more palladium on activated carbon and stir at RT under a hydrogen atmosphere for a further 24 h. Filter the catalyst off and concentrate the solution under reduced pressure. 229 mg (37.1% of theory) of the target product are obtained.

1. customthe reaction
2. stirringstir at RT under a hydrogen atmosphere for a further 24 h
3. filtrationFilter the catalyst off and
4. concentrationconcentrate the solution under reduced pressure
5. custom229 mg (37.1% of theory) of the target product are obtained