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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218909Generated: October 29, 2026

N-(3-Aminopropyl)morpholine → 3-[(2-fluoro-4-iodophenyl)amino]-N-(3-morpholin-4-ylpropyl)isonicotinamide

https://huagongshe.com/reaction/218909

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-Aminopropyl)morpholineHCID 61055—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
Product3-[(2-fluoro-4-iodophenyl)amino]-N-(3-morpholin-4-ylpropyl)isonicotinamideHCID 11576676—

Reaction Steps

3-[(2-fluoro-4-iodophenyl)amino]-N-(3-morpholin-4-ylpropyl)isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 1.0 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 1.6 mmol of 3-morpholin-4-yl-propylamine. LC/MS [4.66 min; 485 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198457B2
Source datasetuspto-grants-2012_06
ORD IDord-41ec1cd6428e4df1b363b1899b3dde3c
Source noteuspto-grants-2012_06