Dibutyltin oxide → HCID 178488415, compound

Participants

Reaction Steps

Stir a mixture of 100 mg (0.223 mmol) of (3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]-pyrimidin-4-yl]amino}phenoxy)acetonitrile, 383 mg (3.345 mmol) of trimethylsilyl azide and 83.32 mg (0.334 mmol) of di-n-butyltin oxide in 5 ml of toluene at 80° C. overnight. After cooling, filter off the precipitated solid with suction, wash with toluene and dry at 50° C. under high vacuum overnight. 80.1 mg (73.1% of theory) of the target compound are obtained as a whitish solid.

Provenance & Evidence