HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Aminohomopiperidine → N-azepan-1-yl-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Aminohomopiperidine | HCID 22198 | — |
| Reactant | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| Product | N-azepan-1-yl-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide | HCID 57649645 | — |
Reaction Steps
N-azepan-1-yl-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.45 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 6.2 mmol of azepan-1-ylamine. LC/MS [8.99 min; 455 (M+1)]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198457B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-2591e7a6362b4696b0d6b308e6a8dcff |
| Source note | uspto-grants-2012_06 |