HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Aminomethyl)Benzoic Acid → 4-[({3-[(2-Fluoro-4-iodophenyl)amino]isonicotinoyl}amino)methyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Aminomethyl)Benzoic Acid | HCID 65526 | — |
| Reactant | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| Product | 4-[({3-[(2-Fluoro-4-iodophenyl)amino]isonicotinoyl}amino)methyl]benzoic acid | HCID 11720125 | — |
Reaction Steps
4-[({3-[(2-fluoro-4-iodophenyl)amino]isonicotinoyl}amino)methyl]benzoic acid was synthesized according to the procedure for General Method 1, outlined above, starting with 0.3 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.45 mmol of 4-aminomethylbenzoic acid. LC/MS [9.25 min; 492 (M+1)]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198457B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-3a8bb4d8fdf940ef95efc7e529fa9eb5 |
| Source note | uspto-grants-2012_06 |