HCID 5460540, compound → D-Aspartic Acid

HRID 2189192Notes

Reaction equation

HRID 2189192 reaction equation
[NH2:1][C@@H:2]([C:7]([O-:9])=[O:8])[CH2:3][C:4]([O-:6])=[O:5].C1(N2C3C(=CC(F)=C(N4CC(=NOC)C5(CNC5)C4)N=3)C(=O)C(C(O)=O)=C2)CC1>O>[NH2:1][C@@H:2]([C:7]([OH:9])=[O:8])[CH2:3][C:4]([OH:6])=[O:5]

Participants

4

Reactant 2

HCID 5460540HCID 5460540, compoundHCID 54556623Zabofloxacin

Product 1

HCID 83887D-Aspartic Acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

30 mg of D-aspartate of 1-cyclopropyl-6-fluoro-7-(8-methoxyimino-2,6-diaza-spiro[3.4]oct-6-yl)-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid as prepared in Example 1 is dissolved in 100 ml of distilled water, and then subjected to stability test at room temperature. The results are shown in Table 2.

Workup

  1. customsubjected to stability test at room temperature

Sources & evidence

ORD record
ord-d49818eeec054da3813afd847b906945
Source dataset
uspto-grants-2012_12
Patent number
US08324238B2

Reaction notes

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