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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2189224Generated: November 1, 2026

2-Methoxybenzoyl chloride → HCID 135921467, compound

https://huagongshe.com/reaction/2189224

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methoxybenzoyl chlorideHCID 88969—
Reactanttert-butyl (3S)-3-aminopiperidine-1-carboxylateHCID 1501975—
Reactant1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 2773987—
Reactant2-Amino-4-bromobenzonitrileHCID 9920636—
ProductHCID 135921467HCID 135921467—

Reaction Steps

The title compound was prepared from 2-methoxybenzoyl chloride, 2-amino-4-bromobenzonitrile, (S)-3-amino-piperidine-1-carboxylic acid tert-butyl ester and 1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole using methods analogous to those described in Synthesis 72.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324226B2
Source datasetuspto-grants-2012_12
ORD IDord-3e6487d05ca8427ab79fddafc680b83e
Source noteuspto-grants-2012_12