HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl (3S)-3-aminopiperidine-1-carboxylate → HCID 135921473, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl (3S)-3-aminopiperidine-1-carboxylate | HCID 1501975 | — |
| Reactant | 2-Amino-4-bromobenzonitrile | HCID 9920636 | — |
| Reactant | tert-butyl 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate | HCID 16217654 | — |
| Reactant | 5-Fluoro-2-Methoxybenzoyl chloride | HCID 22100460 | — |
| Product | HCID 135921473 | HCID 135921473 | — |
Reaction Steps
The title compound was prepared from 5-fluoro-2-methoxybenzoyl chloride, 2-amino-4-bromobenzonitrile, (S)-3-amino-piperidine-1-carboxylic acid tert-butyl ester and tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate using methods analogous to those described in Synthesis 72.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324226B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-7202d80ac4184cdf86d5ac63afe51413 |
| Source note | uspto-grants-2012_12 |