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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2189227Generated: October 29, 2026

HCID 136068452, compound → HCID 135921477, compound

https://huagongshe.com/reaction/2189227

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 136068452HCID 136068452—
ReactantHCID 136398357HCID 136398357—
ProductHCID 135921477HCID 135921477—

Reaction Steps

The title compound was prepared using methods analogous to those described in Synthesis 59, replacing (S)-tert-butyl 3-(6-bromo-2-(2-hydroxyphenyl)quinazolin-4-ylamino)pyrrolidine-1-carboxylate with (S)-tert-butyl 3-(7-bromo-2-(5-fluoro-2-hydroxyphenyl)quinazolin-4-ylamino)pyrrolidine-1-carboxylate in Synthesis 59-A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324226B2
Source datasetuspto-grants-2012_12
ORD IDord-dc529dc401ed42e788d3e13e9eaf61b3
Source noteuspto-grants-2012_12