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Cyclopropanemethanamine → N-(cyclopropylmethyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclopropanemethanamine | HCID 75646 | — |
| 反応物 | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| 生成物 | N-(cyclopropylmethyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide | HCID 11567754 | — |
反応手順
N-(cyclopropylmethyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.2 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.23 mmol of cyclopropylmethylamine. LC/MS [9.79 min; 412 (M+1)]
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08198457B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-1c0824cfb30149a28f1f1149ada4dbe4 |
| 出典メモ | uspto-grants-2012_06 |