HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-3-butyn-2-ol → HCID 136068489, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-3-butyn-2-ol | HCID 8258 | — |
| Reactant | HCID 136068452 | HCID 136068452 | — |
| Reactant | HCID 136068485 | HCID 136068485 | — |
| Reactant | HCID 136337398 | HCID 136337398 | — |
| Product | HCID 136068489 | HCID 136068489 | — |
Reaction Steps
The title compound was prepared using methods analogous to those described in Synthesis 59 and 60, replacing propargyl alcohol and (S)-tert-butyl 3-(6-bromo-2-(2-hydroxyphenyl)quinazolin-4-ylamino)pyrrolidine-1-carboxylate with dimethyl propargyl alcohol and (S)-tert-butyl 3-(6-bromo-2-(5-fluoro-2-hydroxyphenyl)quinazolin-4-ylamino)pyrrolidine-1-carboxylate in Synthesis 59-A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324226B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-171508751b904f56a63d9910385abf9f |
| Source note | uspto-grants-2012_12 |