HCID 3626675, compound → HCID 56924069, compound

Participants

Reaction Steps

The title compound was prepared using a method analogous to that described in Synthesis 52, replacing 4-chloro-2-(2-methoxyphenyl)quinazoline with 4-bromo-2-(4-chloroquinazolin-2-yl)phenol and tert-butyl-3-aminoazepane-1-carboxylate with (3R,4S)-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate. (3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate was prepared as described in J. Am. Chem. Soc., 2006, 10638.

Provenance & Evidence