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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2189308Generated: October 29, 2026

Cyclopentylamine → 2-Chloro-7-cyclopentyl-6-methyl-7H-pyrrolo[2,3-d]pyrimidine

https://huagongshe.com/reaction/2189308

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentylamineHCID 2906—
Reactant5-Bromo-2,4-dichloropyrimidineHCID 289973—
Reactant2-Chloro-6-methyl-7-(pentan-3-yl)-7H-pyrrolo[2,3-d]pyrimidineHCID 58015815—
Product2-Chloro-7-cyclopentyl-6-methyl-7H-pyrrolo[2,3-d]pyrimidineHCID 84819779—

Reaction Steps

2-Chloro-7-cyclopentyl-6-methyl-7H-pyrrolo[2,3-d]pyrimidine is prepared from cyclopentyl amine and 5-bromo-2,4-dichloropyrimidine using a method similar to that for the preparation of 2-chloro-7-(1-ethyl-propyl)-6-methyl-7H-pyrrolo[2,3-d]pyrimidine. given in example 328.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324225B2
Source datasetuspto-grants-2012_12
ORD IDord-bb82a29173fe4dfd8c2cab4b7ed5be87
Source noteuspto-grants-2012_12