HRID2189368

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：NC(=O)CNS(=O)(=O)c1ccccc1[N+](=O)[O-]

HCID23078895

N~2~-(2-Nitrobenzene-1-sulfonyl)glycinamide

C8H9N3O5S

结构：CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(C)C)c2Cc2ccc(OCCCO)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

HCID68942902

未命名化合物

结构：C[C@H](NS(=O)(=O)c1ccccc1[N+](=O)[O-])C(N)=O

HCID68945906

未命名化合物

PRODUCTS

生成物

结构：CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(C)C)c2Cc2ccc(OCCCN[C@@H](C)C(N)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

HCID68942574

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a similar manner to that described in Example 39 using 3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-4-{[4-(3-hydroxypropoxy)phenyl]-methyl}-5-isopropyl-1H-pyrazole and (S)-2-(2-nitrobenzenesulfonylamino)propionamide instead of 3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-4-{[4-(3-hydroxypropoxy)-2-methylphenyl]methyl}-5-isopropyl-1H-pyrazole and 2-(2-nitrobenzenesulfonylamino)acetoamide, respectively.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f0b81ebbf0d749539c81be5e48592427
来源数据集: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08324176B2
来源说明: uspto-grants-2012_12

反应 SMILES

[C:1]([O:4][C@@H:5]1[C@@H:10]([O:11][C:12](=[O:14])[CH3:13])[C@H:9]([O:15][C:16](=[O:18])[CH3:17])[C@@H:8]([CH2:19][O:20][C:21](=[O:23])[CH3:22])[O:7][C@H:6]1[O:24][C:25]1[C:29]([CH2:30][C:31]2[CH:36]=[CH:35][C:34]([O:37]CCCO)=[CH:33][CH:32]=2)=[C:28]([CH:42]([CH3:44])[CH3:43])[NH:27][N:26]=1)(=[O:3])[CH3:2].[N+](C1C=CC=CC=1S([NH:57][C@@H:58]([CH3:62])[C:59]([NH2:61])=[O:60])(=O)=O)([O-])=O.[N+]([C:66]1[CH:71]=CC=C[C:67]=1S(NCC(N)=O)(=O)=O)([O-])=O>>[C:1]([O:4][C@@H:5]1[C@@H:10]([O:11][C:12](=[O:14])[CH3:13])[C@H:9]([O:15][C:16](=[O:18])[CH3:17])[C@@H:8]([CH2:19][O:20][C:21](=[O:23])[CH3:22])[O:7][C@H:6]1[O:24][C:25]1[C:29]([CH2:30][C:31]2[CH:36]=[CH:35][C:34]([O:37][CH2:67][CH2:66][CH2:71][NH:57][C@H:58]([C:59](=[O:60])[NH2:61])[CH3:62])=[CH:33][CH:32]=2)=[C:28]([CH:42]([CH3:43])[CH3:44])[NH:27][N:26]=1)(=[O:3])[CH3:2]