Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2189376Generated: October 30, 2026

2-Amino-2-methyl-1-propanol → 3-(beta-D-Glucopyranosyloxy)-4-[(4-(2-[2-hydroxy-1-(hydroxymethyl)ethylamino]ethoxy)-2-methylphenyl)methyl]-5-isopropyl-1H-pyrazole

https://huagongshe.com/reaction/2189376

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-2-methyl-1-propanolHCID 11807—
ReactantSerinolHCID 68294—
ReactantHCID 68941620HCID 68941620—
Product3-(beta-D-Glucopyranosyloxy)-4-[(4-(2-[2-hydroxy-1-(hydroxymethyl)ethylamino]ethoxy)-2-methylphenyl)methyl]-5-isopropyl-1H-pyrazoleHCID 68942745—

Reaction Steps

The title compound was prepared in a similar manner to that described in Example 57 using 3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-4-{[4-(2-hydroxyethoxy)-2-methylphenyl]methyl}-5-isopropyl-1H-pyrazole and 2-amino-1,3-propanediol instead of 3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-4-{[4-(3-hydroxypropoxy)-2-methylphenyl]-methyl}-5-isopropyl-1H-pyrazole and 2-amino-2-methyl-1-propanol, respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324176B2
Source datasetuspto-grants-2012_12
ORD IDord-145eac6fa5d2423398db796541e3dde7
Source noteuspto-grants-2012_12