HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Methylhydroxylamine → N-methoxy-3-(2-chloro-4-iodo-phenylamino)-isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Methylhydroxylamine | HCID 4113 | — |
| Reactant | 3-[(2-Chloro-4-iodophenyl)amino]isonicotinic acid | HCID 57649651 | — |
| Product | N-methoxy-3-(2-chloro-4-iodo-phenylamino)-isonicotinamide | HCID 11589486 | — |
Reaction Steps
N-methoxy-3-(2-chloro-4-iodo-phenylamino)-isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.30 mmol of 3-[(2-chloro-4-iodophenyl)amino]isonicotinic acid (intermediate 2) and 0.42 mmol of O-methyl-hydroxylamine. LC/MS [8.75 min; 404 (M+1)]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198457B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-803a06a5c72a4b0a83390a64b42968e3 |
| Source note | uspto-grants-2012_06 |