Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218946Generated: October 29, 2026

p-Methylphenethylamine → 3-[(2-fluoro-4-iodophenyl)amino]-N-[2-(4-methylphenyl)ethyl]isonicotinamide

https://huagongshe.com/reaction/218946

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-MethylphenethylamineHCID 76751—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
Product3-[(2-fluoro-4-iodophenyl)amino]-N-[2-(4-methylphenyl)ethyl]isonicotinamideHCID 11712599—

Reaction Steps

3-[(2-fluoro-4-iodophenyl)amino]-N-[2-(4-methylphenyl)ethyl]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.54 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.62 mmol of 2-(4-methylphenyl)ethylamine. LC/MS [10.25 min; 476 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198457B2
Source datasetuspto-grants-2012_06
ORD IDord-6167f17c484f494b942c325ea0f7d4ce
Source noteuspto-grants-2012_06