Dicyclohexylcarbodiimide → HCID 24894071, compound

Participants

Reaction Conditions

Reaction Steps

The 6-(2-chloropyridine-3-yloxy)-pyridine-3-amine (200 mg, 0.9 mmol) and indole-3-carboxylic acid (150 mg, 0.9 mmol) were dissolved in DMF (5 ml), DCC (200 mg, 0.99 mmol) was added to the solution, and then the mixture was stirred at 70° C. for 8 hours. After the reaction was completed, the product was washed and filtered to yield a target compound as a white solid (200 mg, 61%) by chromatography (methanol:dichloromethane=1:30).

Provenance & Evidence