Dicyclohexylcarbodiimide → HCID 44250363, compound

Participants

Reaction Conditions

Reaction Steps

The 6-(2-bromopyridine-3-yloxy)pyridine-3-amine (200 ml, 1.24 mmol) and indole-3-carboxylic acid (200 mg, 1.24 mmol) were dissolved in DMF (5 ml), DCC (280 mg, 1.37 mmol) was added to the solution, and then the mixture was stirred at 60° C. for 8 hours. After the reaction was completed, the product was washed and filtered to yield a target compound as a white solid (100 mg, 20%) by chromatography (methanol:dichloromethane=1:30).

Provenance & Evidence