Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Aminopyridine | HCID 10009 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | Indole-3-Carboxylic Acid | HCID 69867 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 43399328 | HCID 43399328 | 42% |
Reaction Steps
3-aminopyridine (290 mg, 3.1 mmol) and indole-3-carboxylic acid (500 mg, 3.1 mmol) was dissolved in DMF (20 ml), DCC (579 mg, 3.1 mmol) was added to the solution, and then the mixture was stirred at 60° C. for 8 hours. After the reaction was completed, the product was washed and filtered to yield a target compound as a white solid (300 mg, 42%) by chromatography (methanol:dichloromethane=1:20).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08324246B2 |
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| Source dataset | uspto-grants-2012_12 |
|---|
| ORD ID | ord-058bcaf89a3541c0ba61922643efdeab |
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| Source note | uspto-grants-2012_12 |
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