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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2189481Generated: October 29, 2026

3-Aminopyridine → HCID 43399328, compound

https://huagongshe.com/reaction/2189481

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-AminopyridineHCID 10009—
ReactantDicyclohexylcarbodiimideHCID 10868—
ReactantIndole-3-Carboxylic AcidHCID 69867—
SolventDimethylformamideHCID 6228—
ProductHCID 43399328HCID 4339932842%

Reaction Conditions

Temperature60 °C

Reaction Steps

3-aminopyridine (290 mg, 3.1 mmol) and indole-3-carboxylic acid (500 mg, 3.1 mmol) was dissolved in DMF (20 ml), DCC (579 mg, 3.1 mmol) was added to the solution, and then the mixture was stirred at 60° C. for 8 hours. After the reaction was completed, the product was washed and filtered to yield a target compound as a white solid (300 mg, 42%) by chromatography (methanol:dichloromethane=1:20).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324246B2
Source datasetuspto-grants-2012_12
ORD IDord-058bcaf89a3541c0ba61922643efdeab
Source noteuspto-grants-2012_12