HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2189482Generated: October 29, 2026
Dicyclohexylcarbodiimide → HCID 44250433, compound
https://huagongshe.com/reaction/2189482
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | Indole-3-Carboxylic Acid | HCID 69867 | — |
| Reactant | 3-(Pyridin-3-yl)aniline | HCID 459521 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 44250433 | HCID 44250433 | 55% |
Reaction Steps
The crude 3-pyridine-3-yl-phenylamine (60 mg, 0.35 mmol) and indole-3-carboxylic acid (57 mg, 0.35 mmol) were dissolved in DMF (3 ml), DCC (73 mg, 0.35 mmol) was added to the solution, and then the mixture was stirred at 80° C. for 8 hours. After the reaction was completed, the product was washed and filtered to yield a target compound as a white solid (60 mg, 55%) by chromatography (methanol:dichloromethane=1:20).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08324246B2 |
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| Source dataset | uspto-grants-2012_12 |
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| ORD ID | ord-4c58df97a81f4524a4d10d510a333e06 |
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| Source note | uspto-grants-2012_12 |
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