HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 1-benzyl-1H-indol-6-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 6-Nitro-1H-indole | HCID 78502 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-benzyl-1H-indol-6-amine | HCID 22019562 | — |
Reaction Steps
1-Benzyl-1H-indol-6-ylamine (B-2) was synthesized following the general scheme above starting from 6-nitroindole and benzyl bromide. Overall yield (˜40%). HPLC ret. time 2.19 min, 10-99% CH3CN, 5 min run; ESI-MS 223.3 m/z (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324242B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-3be7b707395e477b818fdb6703921623 |
| Source note | uspto-grants-2012_12 |