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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218957Generated: October 30, 2026

3-Methoxyaniline → 3-[(2-fluoro-4-iodophenyl)amino]-N-(3-methoxyphenyl)isonicotinamide

https://huagongshe.com/reaction/218957

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxyanilineHCID 10824—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
Product3-[(2-fluoro-4-iodophenyl)amino]-N-(3-methoxyphenyl)isonicotinamideHCID 11648339—

Reaction Steps

3-[(2-fluoro-4-iodophenyl)amino]-N-(3-methoxyphenyl)isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.31 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.46 mmol of 3-methoxyaniline. LC/MS [6.40 min; 464 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198457B2
Source datasetuspto-grants-2012_06
ORD IDord-d0997c15b0ef4e268e1c02e1d9cbf19c
Source noteuspto-grants-2012_06