Ethyl 4,5-dibromofuran-2-carboxylate → Ethyl 4-bromofuran-2-carboxylate

HRID 2190114Notes

Reaction equation

HRID 2190114 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[O:5][C:6]=1Br.BrC1C=C(C(O)=O)OC=1>>[Br:1][C:2]1[CH:3]=[C:4]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[O:5][CH:6]=1

Participants

3

Reactant 2

HCID 5161728Ethyl 4,5-dibromofuran-2-carboxylateHCID 122394464-Bromofuran-2-carboxylic acid

Product 1

HCID 58064765Ethyl 4-bromofuran-2-carboxylate

Procedure

The preparation of the title compound takes place on analogy to the synthesis of the compound from Example 2A starting with the compound from Example 1A. 19.1 g (89% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-9e3b351125084b53bed64b02929ffb61
Source dataset
uspto-grants-2012_12
Patent number
US08324268B2

Reaction notes

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