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HRID2190120

反应详情

EQUATION

反应方程式

HRID 2190120 的结构方程式

REACTANTS

反应物

2
反应SMILES：CCOC(=O)c1cc(Br)c(-c2cccc(Cl)c2)o1
HCID58064772

未命名化合物

反应SMILES：CCOC(=O)c1cc(-c2cc(F)cc(Cl)c2)c(-c2cccc(C#N)c2)o1
HCID58064795

未命名化合物

PRODUCTS

产物

1
反应SMILES：CCOC(=O)c1cc(-c2cccc(Cl)c2)c(-c2cccc(Cl)c2)o1
HCID58064774

未命名化合物

PROCEDURE

实验过程

The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 11A starting with the compound from Example 5A. Extraction is carried out with dichloromethane and purification is by preparative HPLC (RP18 column; eluent: acetonitrile/water gradient). 452 mg (34% of theory) of the title compound are obtained.

WORKUP

后处理

  1. extractionExtraction
  2. customis carried out with dichloromethane and purification