HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 5-bromo-4-(3-chlorophenyl)furan-2-carboxylate → 5-Bromo-4-(3-chlorophenyl)furan-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 5-bromo-4-(3-chlorophenyl)furan-2-carboxylate | HCID 58064768 | — |
| Reactant | 4-(3-Chloro-5-fluorophenyl)-5-(3-cyanophenyl)furan-2-carboxylic acid | HCID 58064798 | — |
| Product | 5-Bromo-4-(3-chlorophenyl)furan-2-carboxylic acid | HCID 58064802 | — |
Reaction Steps
The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 20A starting with the compound from Example 18A. The crude product obtained after extraction is dried under high vacuum and reacted further without chromatographic purification. 47.0 mg (86% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324268B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-d95bb25cf0934d10b758a3700952141b |
| Source note | uspto-grants-2012_12 |