HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-{[5-Bromo-4-(3-chlorophenyl)furan-2-yl]carbonyl}imidazolidin-4-one → 5-{3-(3-Chlorophenyl)-5-[(4-oxoimidazolidin-1-yl)carbonyl]furan-2-yl}-2-fluorobenzenecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-{[5-Bromo-4-(3-chlorophenyl)furan-2-yl]carbonyl}imidazolidin-4-one | HCID 58064769 | — |
| Reactant | 1-{[5-(3-Chloro-4-fluorophenyl)-4-(3-chlorophenyl)furan-2-yl]carbonyl}imidazolidin-4-one | HCID 58064805 | — |
| Product | 5-{3-(3-Chlorophenyl)-5-[(4-oxoimidazolidin-1-yl)carbonyl]furan-2-yl}-2-fluorobenzenecarbonitrile | HCID 58064784 | — |
Reaction Steps
The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 25 starting with the compound from Example 30A. 11.0 mg (20% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324268B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-e3531592715a40419e6571595aaa23ef |
| Source note | uspto-grants-2012_12 |