Dimethyldioxirane → HCID 54575146, compound

Participants

Reaction Steps

5-allyl-2-(4-fluorophenyl)-N-methyl-6-(N-methylmethylsulfonamido)furo[2,3-b]pyridine-3-carboxamide was stirred with a solution of dimethyldioxirane in acetone until LCMS indicated complete conversion to product. The solution was evaporated to dryness to afford the title compound. MS (ESI) m/z 434.1 (M+1). NMR (400 MHz, CD3CN) δ 8.23 (s, 1H), 8.04-8.00 (m, 2H), 7.33-7.29 (m, 2H), 6.83 (br s, 1H), 3.28 (s, 3H), 3.26-3.24 (m, 2H), 3.16 (s, 3H), 3.05-2.99 (m, 1H), 2.92-2.90 (d, 3H), 2.82-2.79 (m, 1H), 2.63-2.61 (m, 1H)

Provenance & Evidence