HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium vinyltrifluoroborate → 2-(4-Fluorophenyl)-N-methyl-6-(methylsulfonamido)-5-vinylfuro[2,3-b]pyridine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium vinyltrifluoroborate | HCID 23679353 | — |
| Reactant | 2-(4-fluorophenyl)-N-methyl-6-(methylsulfonamido)-5-(prop-1-en-2-yl)furo[2,3-b]pyridine-3-carboxamide | HCID 58052333 | — |
| Product | 2-(4-Fluorophenyl)-N-methyl-6-(methylsulfonamido)-5-vinylfuro[2,3-b]pyridine-3-carboxamide | HCID 58052406 | — |
Reaction Steps
2-(4-Fluorophenyl)-N-methyl-6-(methylsulfonamido)-5-vinylfuro[2,3-b]pyridine-3-carboxamide is prepared by analogy to 2-(4-Fluorophenyl)-N-methyl-6-(methylsulfonamido)-5-(prop-1-en-2-yl)furo[2,3-b]pyridine-3-carboxamide, step A of Example 33. Potassium vinyltrifluoroborate may be used as the coupling partner.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324239B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-0d4874ac7060420095e3de909d426679 |
| Source note | uspto-grants-2012_12 |