(2-Nitrophenyl)boronic acid → (2-Aminophenyl)boronic acid

Participants

Reaction Steps

To a solution of 2-nitrophenylboronic acid (500 mg, 2.99 mmol) and MeOH (10 mL) was added 10% Pd/C (250 mg). The mixture was stirred under hydrogen at atmospheric pressure for 2 hours. The catalyst was removed by filtration through diatomaceous earth and the filtrate was concentrated under reduced pressure. The residue was purified by column chromatography (silica, 0-50% CMA in CH2Cl2) to afford the sub-title compound (182 mg, 44%).

Provenance & Evidence