HCID 2996663, compound → HCID 28391877, compound

HRID 2190427Notes

Reaction equation

HRID 2190427 reaction equation
C([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([C:11]([NH:13][C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([C:20]([F:23])([F:22])[F:21])[CH:15]=2)=[O:12])[CH:6]=1)(=O)C>[OH-].[Na+]>[OH:4][C:5]1[CH:6]=[C:7]([CH:8]=[CH:9][CH:10]=1)[C:11]([NH:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([C:20]([F:21])([F:22])[F:23])[CH:15]=1)=[O:12]

Participants

3

Reactant 1

HCID 2996663HCID 2996663, compound

Product 1

HCID 28391877HCID 28391877, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

Using 3-({[3-(trifluoromethyl)phenyl]amino}carbonyl)phenyl acetate (16.2 g, 50 mmol) and 8N aqueous sodium hydroxide solution (10 mL), and in the same manner as in Example A25(ii), the title compound (13.9 g, 99%) was obtained as a white powder.

Sources & evidence

ORD record
ord-04604448cd0340ac86c7a4edfd937824
Source dataset
uspto-grants-2012_12
Patent number
US08324395B2

Reaction notes

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