HCID 67312049, compound → HCID 67312567, compound

HRID 2190429Notes

Reaction equation

HRID 2190429 reaction equation
[N+:1]([C:4]1[CH:29]=[CH:28][C:7]([O:8][C:9]2[CH:10]=[C:11]([CH:25]=[CH:26][CH:27]=2)[C:12]([NH:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([C:21]([F:24])([F:23])[F:22])[CH:16]=2)=[O:13])=[CH:6][CH:5]=1)([O-])=O>[C].[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([O:8][C:9]2[CH:10]=[C:11]([CH:25]=[CH:26][CH:27]=2)[C:12]([NH:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([C:21]([F:22])([F:23])[F:24])[CH:16]=2)=[O:13])=[CH:28][CH:29]=1

Participants

3

Reactant 1

HCID 67312049HCID 67312049, compound

Product 1

HCID 67312567HCID 67312567, compoundYield 69%

Reagents, catalysts & solvents 1

HCID 178418390HCID 178418390, compoundCatalyst

Procedure

Using 3-(4-nitrophenoxy)-N-[3-(trifluoromethyl)phenyl]benzamide (2.81 g, 10.0 mmol) and 10%-palladium carbon (1 g), and in the same manner as in Example A25(iv), the title compound (2.45 g, 69%) was obtained as a brown oil.

Sources & evidence

ORD record
ord-fa4f97498fa14c3ea70470ea706f3f8b
Source dataset
uspto-grants-2012_12
Patent number
US08324395B2

Reaction notes

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