HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 57387819, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | tert-butyl N-(3-hydroxyphenyl)carbamate | HCID 312485 | — |
| Reactant | 5-fluoro-N-methyl-2-nitroaniline | HCID 22905774 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 57387819 | HCID 57387819 | 120.4% |
Reaction Steps
Using tert-butyl (3-hydroxyphenyl)carbamate (11.0 g, 52.3 mmol) produced in Example C1(i), 5-fluoro-N-methyl-2-nitroaniline (8.58 g, 50.4 mmol), N,N-dimethylformamide (200 ml) and potassium carbonate (28.6 g, 207 mmol) as starting materials, and in the same manner as in Example C1(ii) except that the reaction temperature was set to 80° C., the title compound (21.8 g) was obtained as an orange syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324395B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-95dfe627d2bd4017a42e7e7837347c83 |
| Source note | uspto-grants-2012_12 |