HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[4-(3-Tert-butyl-phenylcarbamoyl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester → N-(3-tert-Butyl-phenyl)-4-piperazin-1-yl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[4-(3-Tert-butyl-phenylcarbamoyl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester | HCID 59318017 | — |
| Reactant | N-(4-tert-Butyl-phenyl)-6-piperazin-1-yl-nicotinamide | HCID 59318019 | — |
| Product | N-(3-tert-Butyl-phenyl)-4-piperazin-1-yl-benzamide | HCID 59318141 | — |
Reaction Steps
N-(3-tert-Butyl-phenyl)-4-piperazin-1-yl-benzamide was prepared from 4-[4-(3-tert-butyl-phenylcarbamoyl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester in a manner similar to the one described in the synthesis of N-(4-tert-butyl-phenyl)-6-piperazin-1-yl-nicotinamide above. HRMS m/z calcd for C21H27N3O [M+H]+: 338.2225. Found: 338.2227.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324385B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-bd8a24a1be08454fa3b6c4d3b32f6005 |
| Source note | uspto-grants-2012_12 |