HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl piperazine-1-carboxylate → N-(3-tert-Butyl-phenyl)-2-methyl-4-piperazin-1-yl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | N-(3-tert-Butyl-phenyl)-3-fluoro-4-piperazin-1-yl-benzamide | HCID 59318037 | — |
| Reactant | 4-bromo-N-(3-tert-butyl-phenyl)-2-methyl-benzamide | HCID 59318096 | — |
| Product | N-(3-tert-Butyl-phenyl)-2-methyl-4-piperazin-1-yl-benzamide | HCID 59318133 | — |
Reaction Steps
N-(3-tert-Butyl-phenyl)-2-methyl-4-piperazin-1-yl-benzamide was synthesized from 4-bromo-N-(3-tert-butyl-phenyl)-2-methyl-benzamide and piperazine-1-carboxylic acid tert-butyl ester in a manner similar to the one described in the synthesis of N-(3-tert-butyl-phenyl)-3-fluoro-4-piperazin-1-yl-benzamide above. LCMS calcd for C22H29N3O (m/e) 351, obsd 352 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324385B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-3004f5c7054c4d92baccc6be4ebe2cd5 |
| Source note | uspto-grants-2012_12 |