反应详情

4-{4-[5-(4-Methoxy-2-methyl-phenylcarbamoyl)-pyridin-2-yl}-piperazin-1-yl]-benzoic acid was prepared from 4-piperazin-1-yl-benzoic acid benzyl ester and 6-chloro-N-(4-methoxy-2-methyl-phenyl)-nicotinamide with a method similar to the one described in the synthesis of 4-[4-(5-phenylcarbamoyl-pyridin-2-yl)-piperazin-1-yl]-benzoic acid above. HRMS m/z calcd for C25H26N4O4 [M+H]+: 447.2027. Found: 447.2027.