HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-chlorobenzoic acid → HCID 59318004, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-chlorobenzoic acid | HCID 12594302 | — |
| Reactant | N-(3-tert-Butyl-phenyl)-4-piperidin-4-yl-benzamide | HCID 59317976 | — |
| Reactant | 4-{4-[4-(3-tert-Butyl-phenylcarbamoyl)-2-fluoro-phenyl]-piperazin-1-yl}-benzoic acid | HCID 59318193 | — |
| Product | HCID 59318004 | HCID 59318004 | — |
Reaction Steps
4-{4-[4-(3-tert-Butyl-phenylcarbamoyl)-phenyl]-piperidin-1-yl}-3-chloro-benzoic acid was synthesized from N-(3-tert-butyl-phenyl)-4-piperidin-4-yl-benzamide and 4-bromo-3-chloro-benzoic acid in a manner similar to the one described in the synthesis of 4-{4-[4-(3-tert-butyl-phenylcarbamoyl)-2-fluoro-phenyl]-piperazin-1-yl}-benzoic acid above. LCMS calcd for C29H31ClN2O3 (m/e) 490, obsd 491 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324385B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-6f0d5d3df0ce49bc8fb705de6dfa1905 |
| Source note | uspto-grants-2012_12 |