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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2190624Generated: November 1, 2026

4-Bromo-2-fluorobenzoic acid → HCID 59317985, compound

https://huagongshe.com/reaction/2190624

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-fluorobenzoic acidHCID 302681—
ReactantN-(3-tert-Butyl-phenyl)-4-piperidin-4-yl-benzamideHCID 59317976—
Reactant4-{4-[4-(3-tert-Butyl-phenylcarbamoyl)-2-fluoro-phenyl]-piperazin-1-yl}-benzoic acidHCID 59318193—
ProductHCID 59317985HCID 59317985—

Reaction Steps

4-{4-[4-(3-tert-Butyl-phenylcarbamoyl)-phenyl]-piperidin-1-yl}-2-fluoro-benzoic acid was synthesized from N-(3-tert-butyl-phenyl)-4-piperidin-4-yl-benzamide and 4-bromo-2-fluoro-benzoic acid in a manner similar to the one described in the synthesis of 4-{4-[4-(3-tert-butyl-phenylcarbamoyl)-2-fluoro-phenyl]-piperazin-1-yl}-benzoic acid above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324385B2
Source datasetuspto-grants-2012_12
ORD IDord-5f3612bae9ed4e5fa5462a9f64d18fb9
Source noteuspto-grants-2012_12