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HRID2190648

反应详情

EQUATION

反应方程式

HRID 2190648 的结构方程式

REACTANTS

反应物

3
结构：CC1(C)CC(=O)OC1=O
HCID87067

2,2-Dimethylsuccinic anhydride

C6H8O3

结构：Cc1cc(NC(=O)c2ccc(N3CCN(C(=O)CC(C)(C)C(=O)O)CC3)nc2)ccc1I
HCID59318056

未命名化合物

结构：Cc1ccc(NC(=O)c2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)nc2)cc1I
HCID59318184

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(NC(=O)c2ccc(N3CCN(C(=O)CC(C)(C)C(=O)O)CC3)nc2)cc1I
HCID59318087

未命名化合物

PROCEDURE

实验过程

4-{4-[5-(3-Iodo-4-methyl-phenylcarbamoyl)-pyridin-2-yl]-piperazin-1-yl}-2,2-dimethyl-4-oxo-butyric acid was prepared from 4-[5-(3-iodo-4-methyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester and 2,2-dimethysuccinic anhydride following a procedure similar to the one described in the synthesis of 4-{4-[5-(4-iodo-3-methyl-phenylcarbamoyl)-pyridin-2-yl]-piperazin-1-yl}-dimethyl-4-oxo-butyric acid above. HRMS m/z calcd for C23H27N4O4I [M+H]+: 551.1150. Found: 551.1152.