HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Dimethylsuccinic anhydride → 4-{4-[4-(3-tert-Butyl-phenylcarbamoyl)-phenyl]-piperazin-1-yl}-2,2-dimethyl-4-oxo-butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Dimethylsuccinic anhydride | HCID 87067 | — |
| Reactant | N-(3-tert-Butyl-phenyl)-4-piperazin-1-yl-benzamide | HCID 59318141 | — |
| Product | 4-{4-[4-(3-tert-Butyl-phenylcarbamoyl)-phenyl]-piperazin-1-yl}-2,2-dimethyl-4-oxo-butyric acid | HCID 59318028 | — |
Reaction Steps
4-{4-[4-(3-tert-Butyl-phenylcarbamoyl)-phenyl]-piperazin-1-yl}-2,2-dimethyl-4-oxo-butyric acid was prepared from 2,2-dimethylsuccinic anhydride and N-(3-tert-butyl-phenyl)-4-piperazin-1-yl-benzamide. HRMS m/z calcd for C27H35N3O4 [M+H]+: 466.2701. Found: 466.2698.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324385B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-21b33d04b261442dbb65e77c49a6ce32 |
| Source note | uspto-grants-2012_12 |