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HRID2190667

反应详情

EQUATION

反应方程式

HRID 2190667 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)N=C=O
HCID62412

tert-Butyl isocyanate

C5H9NO

结构：Cc1ccc(NC(=O)c2ccc(N3CCNCC3)nc2)cc1I
HCID59318071

未命名化合物

结构：CCOC(=O)CCNC(=O)N1CCN(c2ccc(C(=O)Nc3ccc(C)c(I)c3)cn2)CC1
HCID59318118

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(NC(=O)c2ccc(N3CCN(C(=O)NC(C)(C)C)CC3)nc2)cc1I
HCID59318126

未命名化合物

PROCEDURE

实验过程

4-[5-(3-Iodo-4-methyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butylamide was synthesized from N-(3-iodo-4-methyl-phenyl)-6-piperazin-1-yl-nicotinamide and tertbutyl isocyanate in a manner similar to the one described in the synthesis of 3-({4-[5-(3-iodo-4-methyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carbonyl}-amino)-propionic acid ethylester above. LCMS calcd for C22H28IN5O2 (m/e) 521, obsd 522 (M+H).