HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrolein → 2-(3,4-Dimethoxyphenyl)-1,4-pentadien-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrolein | HCID 7847 | — |
| Reactant | 1-Bromo-1-(3,4-dimethoxyphenyl)ethene | HCID 16085361 | — |
| Reactant | HCID 178418306 | HCID 178418306 | — |
| Product | 2-(3,4-Dimethoxyphenyl)-1,4-pentadien-3-ol | HCID 57840757 | 42.3% |
Reaction Steps
According to the General Procedure C, 1-bromo-1-(3,4-dimethoxyphenyl)ethene (1.00 g, 4.11 mmol), t-BuLi (6.05 ml, 10.28 mmol) and acrolein (691 mg, 12.33 mmol) are converted to give after workup and chromatography (SiO2, PE/EE=2:1, Rf=0.25) the title compound (382 mg, 1.74 mmol, 42%) as a yellow oil; C13H16O3 (220.26).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324404B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-1e82c75eb39d417d879060288119d6ee |
| Source note | uspto-grants-2012_12 |